If you are aware of any impending changes to legislation (which might come out of the EU for example), it is vital that you begin to implement the changes to your business immediately to counter any negative impacts.

We now move onto operational impediments that could take more than four years to remove, if indeed they can be removed at all. A solution will depend on the severity of the problem in your particular business and whether a remedy is in your hands or not. Business is losing money

It is vital to tackle this problem immediately, regardless of when you plan to sell. But, losing money is only the effect and you must identify the causes for the losses (which could be any of dozens of reasons) and address those. Because the reasons for losing money are so numerous, it is impossible to suggest a solution to this problem here.